Best weapon in Fallout 4 is a subjective term used to describe the most powerful or effective weapon in the game. There are many different weapons to choose from in Fallout 4, each with its own unique strengths and weaknesses. Some of the most popular and powerful weapons include the Gauss rifle, the minigun, and the Fat Man. The Gauss rifle is a powerful sniper rifle that can take down enemies from a distance, while the minigun is a rapid-fire machine gun that can mow down hordes of enemies. The Fat Man is a nuclear weapon that can deal devastating damage to anything caught in its blast radius.
The best weapon for you will depend on your playstyle and the specific situation you are in. If you prefer to snipe enemies from afar, then the Gauss rifle is a good choice. If you prefer to get up close and personal, then the minigun is a better option. And if you need to deal with a large group of enemies, then the Fat Man is the way to go.